Transcoelomic spread and ovarian seeding during ovulation: A possible pathogenesis of Krukenberg tumor.

Krukenberg tumor is a metastatic ovarian tumor with its primary site being the gastrointestinal tract. The pathogenesis of Krukenberg tumor formation is still in its hypothetical stage though the current understanding suggests lymphatic, hematogenous and transcoelomic as the 3 major routes of metastasis. We believe transcoelomic spread in association with ruptured ovary during the monthly process of ovulation is the major route of metastasis.